The continued development of more efficient and consistent thz emitters in the range of 0. Terahertz thz spectroscopy, and especially thz imaging, holds large potential in the field of nondestructive, contactfree testing. Handheld terahertz imaging david zimdars manager of terahertz research and development inspace ndi technology workshop gillruth center nasa jsc wednesday february 29, 2012. Bowman et al thz imaging of excised breast tumor tissue on paraffin sections 2089. In particular, its high penetration depth into many materials allows the detection of structures underneath the surface without destroying the sample. Exploring dynamics in the farinfrared with terahertz. Schmuttenmaer department of chemistry, yale university, 225 prospect street, p. One area where thz has shown promise and significant growth is the biomedical field2. Mittleman department of electrical and computer engineering, rice university, 6100 main street, houston, texas 77005, usa. Recent advances in terahertz technology for biomedical.
Case report terahertz spectroscopy for cancer diagnosis han li 1, kun zhang3, qian zhou, weiwei mao1. Experimental study of a quasioptic synthetic phasedarray terahertz imaging system by john f. The potential of terahertz imaging for cancer diagnosis. Terahertz imaging with compressed sensing and phase retrieval. Schematic of the experimental setup used for terahertz transmission imaging. These have included advances in ultrafast laser technology and enhancements in terahertz generation and detection ef. However, this speed generally comes at the cost of dynamic range, thus reducing the ability of the system to measure weakly re.
Difference frequency generation between signal and idler pulses in a quasi. Cancer detection in excised breast tumors using terahertz. Thz imaging and sensing for security applications spectra, one may identify the presence of these agents and distinguish them from benign objects. The thz images clearly map out the thz carrier dynamics of the grapheneonsi sample, allowing us to measure sheet conductivity with submm resolution without fabricating electrodes. Reference current is distributed to each row for diode biasing. Terahertz imaging and spectroscopy of large area single. Tremendous strides in thz instrumentation have prompted impressive breakthroughs in thz biomedical research. The challenging world of terahertz radiation and imaging l. Timereversal and modelbased imaging in a thz waveguide malakeh a.
Terahertz imaging principles, techniques, benefits and limitations. Thz production begins at the transmitter, shown in fig. Imaging in the terahertz thz wavelengths was an avenue that. Bajwa excitation of low loss he11 modes on an acupuncturelike needle a.
Diffractionlimited imaging with terahertz radiation over the last 10 years, the majority of research developments in terahertz imaging have made use of terahertz timedomain spectroscopy, in. The contrast and the resolution are confirmed by a theoretical study based on the diffraction in nearfield zone. Thz imaging, rcs, scattering, polarimetry publications. Norris center for ultrafast optical science, university of michigan, 2200 bonisteel boulevard, ann arbor, michigan. Thz versus millimetre wave imaging millimetre wave mmw imaging 6 is a fairly welldeveloped technology. Case report terahertz spectroscopy for cancer diagnosis. Terahertz technology for defense and securityrelated. In contrast to xray, which has similar properties, thz radiation is nonhazardous. Ohara bachelor of science in engineering university of michigan ann arbor, mi usa 1998 submitted to the faculty of the graduate college of oklahoma state university in partial fulfillment of the requirements for the degree of doctor of philosophy. Born morphological study of sweat ducts for the investigation of terahertz waves interaction with human skin s. Optical frequency switching scheme for a highspeed. This month also has the second installment of graduate student fellowsa catchup, entirely written by young researchers.
Electrooptic thz imaging systems14,15 can be used in conjunction with ccd cameras to form whole im ages at once, thus greatly accelerating the imaging pro cess. Terahertz parametric oscillator tpo the mode locked fiber laser pumps the opo with a 10 w average power in 6 picosecond pulses at 1064 nm. Timereversal and modelbased imaging in a thz waveguide. Model object is imaged, and subwavelength spatial resolution is demonstrated for the first time to our knowledge with this configuration. An investigation of thz burn wound edema imaging using mri n. In addition to localization, other techniques attempt to provide assessment of the tumor margin during the surgery. University of connecticut comparison of thz imaging with xray kiarash ahi, navid asadizanjani, sina shahbazmohamadi, mark tehranipoor and mehdi anwar if you want to use these slides, please reference to our work. Thz imaging with respect to many of the proposed industrial and commercial uses.
Terahertz thz technology has many special features that make it attractive for imaging. In this paper, to reduce the array elements for azimuthrange imaging, a onedimensional 1d sparse mimo array is introduced, which combines with the wideband emitted signal to achieve 2d imaging in the near. Technical paper thz spectroscopic imaging at khz pixel rates. Singlechannel prototype terahertz endoscopic system. Our goal was to investigate and develop the fundamentals of a handheld thz imager for concealed weapon detection. In addition to localization, other techniques attempt to provide assessment of the tumor margin during. The present study is devoted to analyzing the propertiesespecially optical propertiesof the thz materials used. Index term terahertz radiation, biomedical imaging system, breast and colon cancer, thztds, terahertz pulse imaging. Pdf terahertz imaging principles, techniques, benefits. Singlechannel prototype terahertz endoscopic system pallavi doradla,a,b, karim alavi,c cecil joseph,a,b and robert gilesa,b auniversity of massachusetts lowell, department of physics, massachusetts 01854, united states bbiomedical terahertz technology center, lowell, massachusetts 01854, united states cuniversity of massachusetts medical school, division of colon and.
This relatively new imaging technique, based on terahertz timedomain spectroscopy, has the potential to be the first portable farinfrared imaging spectrometer. These include optical analysis, radiography, eddy current, ultrasonic and physical measurement. Giles, continuous wave terahertz reflection imaging of human colorectal tissue, in terahertz, rf, millimeter, submillimeterwave technology and applications vi, edited by laurence p. The ongoing advances in the development of thz systems, as well as the appearance of the first related commercial products, indicate that largescale market introduction of thz systems is rapidly approaching. Terahertz thz 10 12 hz radiation has attracted wide attention for its unprecedented sensing ability and its noninvasive and nonionizing properties. Sources of thz radiation are, at this point, very rare in. To live up to its enormous inherent potential, thz imaging has to dramatically increase its acquisition speed without compromising the signal to noise ratio snr of the imaging system. Biomedical applications of terahertz spectroscopy and imaging.
Construct and deliver a prototype compact tdthz reflection tomography nde instrument terahertz thz imaging and spectroscopy of a 15. This thesis presents research in the area of inverse thz imaging architectures via modelbased image reconstruction. In contrast to xray, which has similar properties, thz radiation is. Terahertz technology for defense and securityrelated applications by.
Lowell, ma 01854 abstract the submillimeterwave technology laboratory stl at the university of massachusetts lowell has. Typically, mmw systems operate at a discrete operation frequency of roughly 30 ghz. Sanphuang et al reconfigurable thz filters using phasechange material and integrated heater 585 fig. Terahertz imaging of excised breast tumor tissue on. Realtime thz imaging active terahertz imaging system with realtime frame rates 12 fps operation frequency 812 ghz fully electronic, room temperature f. Optical frequency switching scheme for a highspeed broadband thz measurement system based on the photomixing technique hajun song, sejin hwang, and jongin song department of information and communications, gwangju institute of science and technology gist. Thz imaging and sensing have seen a great deal of activity. Goyette, jerry waldman, high resolution imaging using 325 ghz and 1. Fiberdrawn metamaterial for thz waveguiding and imaging. Thz can look through the coating to the underlying metal to adjust fit. Nicholas wong tracked down five more past recipients of the ieee photonics society grad. Timedomain thz spectroscopy, with its time coherence and extremely broad spectral bandwidth, will continue to expand its reach and range of applications, from spectroscopy of superconductors to subcutaneous imaging of skin cancer. Thz radiation is nonionizing and nondestructive, and exposes minimal health risk, making it suitable for commercial uses such as security scanning and medical imaging.
The challenging world of terahertz radiation and imaging. Quasicw thzimaging based on a highefficiency tunable photonic transmitter jayu lu, hsuhao chang, lijin chen, and mingchun tien graduate institute of electrooptical engineering and department of electrical engineering, national taiwan university, taipei 10617. Delft university of technology thz imaging using uncooled. A new thz imaging system based on a local illumination by a nearfield source is presented. There are many types of automated nondestructive testing ndt systems and processes for ensuring manufactured components are created within specified parameters and without flaws. Therefore, it would be safe and desirable to use thz light for medical imaging for both screening and diagnostic purposes if the technology could be developed appropriately. The authors shown below used federal funds provided by. Exploring dynamics in the farinfrared with terahertz spectroscopy charles a. Onchip low noise baseband amplifiers two scanning modes. Cancer detection in excised breast tumors using terahertz imaging and spectroscopy fig. Much of the interest in terahertz science and technology has grown out of the natural overlap between the electronics and optics points of view. Thz imaging using uncooled wideband direct detection focal plane arrays sven van berkel, student member, ieee, ozan yurduseven, student member, ieee, angelo freni, senior member, ieee, andrea neto, fellow, ieee, and nuria llombart, senior member, ieee invited paper abstractin millimeter and submillimeterwave radiometric imaging systems, a.
Modelbased image reconstruction for thz imaging systems. Tirkel monitoring the water status of plants using thz radiation n. Tray imaging selected topics in quantum electronics. We give several examples which illustrate the possible applications of this technology, using both the amplitude and phase information contained in the thz waveforms. Terahertz thz imaging and spectroscopy has been a rapidly growing area of research in the past decade. Terahertz imaging with compressed sensing and phase retrieval wai lam chan, matthew l. Abstract this thesis deals with chosen aspects of terahertz thz technology that have potential in defense and securityrelated applications. Goyette, and jerry waldman submillimeterwave technology laboratory university of massachusetts lowell 175 cabot st. Imaging of broadband terahertz beams using an array of. Quasicw thzimaging based on a highefficiency tunable. A novel method for simultaneous data acquisition in timeresolved thz. While stationary cabins for thz imaging are in operation, this document is a research report submitted to the u. Mmw detector technology has only now advanced to the point where real time images are possible.
560 210 1492 809 539 386 508 806 1577 761 1181 917 909 401 1017 782 611 159 255 1461 122 404 674 863 1204 1223 704 1447 1545 214 1047 720 1118 83 712 361 1262 741 13 1028 555 978 521 130 256 345